Eventually the chromosome breaks down from the defects.
2.
One such double strand chromosome breaks, this chromosomal rearrangement could be responsible for the other rearrangements.
3.
In time, these nicks also cause full chromosome breaks, which could lead to severe mutations and cancers.
4.
Such chromosome breaks early in an embryo's existence can cause severe birth defects, retardation, and, in some cases, cancer.
5.
Changes in chromosome number may involve even larger mutations, where segments of the DNA within chromosomes break and then rearrange.
6.
Cells deficient in Artemis are more sensitive than normal cells to X rays and they show a higher incidence of chromosome breaks following irradiation.
7.
Translocation is the process by which a piece of one chromosome breaks off and joins another chromosome, or when two chromosomes exchange material when both break.
8.
French is working on the next step, finding exactly what genes are at the point where the chromosomes break; the break presumably makes those genes go haywire.
9.
Chronic myeloid leukemia occurs when pieces of two different chromosomes break off and reattach on the opposite chromosome, forming what is known as the " Philadelphia chromosome ."
10.
It has been suggested ( Carr, 1980, 2000 ) that the " Calycadenia pauciflora " could have originated directly from an ancestral race through a single saltational event involving multiple chromosome breaks.
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